National Open University Exam Past Question BIO 305 October/November 2014

                                                   

        

                                                                  National Open University of Nigeria

                                                            14-16 Ahmadu Bello Way, Victoria Island Lagos 

                                                                      School of science and technology

                                                                October/November 2014 Examination 

                  ^{COURSE CODE: BIO 305}

                  ^{COURSE TITTLE: MOLECULAR BIOLOGY}

                  ^{TIME ALLOWED: 2hrs}

                   ^{Instructions: ANSWER QUESTION 1 AND ANY OTHER 3 QUESTIONS}

^{1. a. Escherichia coli is used as an experimental model in molecular biology . discus                                        9marks}

^{b. List the characteristics of genetic code                                       9marks}

^{c. Describe the structure of the DNA                                                         7marks}

^{2. a. outline the important feature of glycolysis                                                      6marks}

^{b. write short note on the following :}

  ^{i- promoter clearance                                3marks}

^{ii- chain elongation                                        3marks}

^{iii. termination of transcription                               3marks}

^{3. Describe with examples and illustrations the human genetic disorder                                    15marks}

^{4. a. define DNA sequencing                    2marks}

 ^{b. Describe in details any two methods for determining DNA sequences               13marks}

^{5. a. summarize the roles of DNA and RNA                                                         5marks}

^{b. with the help of a good illustration describe the central dogma                     10marks}

^{6. a. write short notes on each of the following :}

^{i- chromosome number                           5marks} 

^{ii- sex chromosomes                                5marks}

^{iii- acistron                       5marks}

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